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Heroin

Price range: €300.00 through €3,000.00

Heroin (diacetylmorphine, CAS 561-27-3) is a high-purity semi-synthetic opioid analytical reference standard for forensic and clinical toxicology . With a molecular formula of C21H23NO5, this white to beige powder is soluble in DMSO and ethanol for analytical workflows . It is intended for LC-MS/MS and GC-MS method development, calibration, and confirmatory analysis of opioids in forensic toxicology, clinical research, and urine drug testing applications .

Key Points

  • Semi-synthetic opioid certified reference material

  • Supplied as high-purity powder

  • Molecular formula: C21H23NO5

  • CAS number: 561-27-3 

  • Soluble in DMSO, ethanol, and acetonitrile for analytical workflows

  • Suitable for LC-MS/MS, HPLC, and GC-MS calibration and validation

  • Intended exclusively for forensic toxicology and analytical research 

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.

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Description

Overview

Heroin, also known as diacetylmorphine or diamorphine, is a semi-synthetic opioid analgesic derived from the acetylation of morphine, a natural alkaloid found in opium . This product is supplied as a high-purity analytical reference standard for use in forensic and clinical toxicology laboratories . As a Schedule I controlled substance under the USDEA, it serves as an essential reference material for the identification and quantification of opioid derivatives in seized materials and biological specimens .

Chemical & Physical Properties

Parameter Value / Description
Chemical name (5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol acetate 
Common product name Heroin Powder
Class Opioid Analgesic (Semi-synthetic)
CAS number 561-27-3 
Molecular formula C21H23NO5 
Molecular weight Approx. 369.41 g/mol 
Typical salt form Free base or hydrochloride hydrate (CAS 1502-95-0) 
Appearance White to beige powder or crystalline solid 
Typical solubility Soluble in DMSO (5 mg/mL), ethanol (6 mg/mL); limited water solubility (<0.2 mg/mL) 
Typical state Powder/Crystalline Solid

The material presents as a white to beige powder or crystalline solid . For analytical preparation, stock solutions are commonly prepared in acetonitrile, DMSO, or ethanol . The compound exhibits limited aqueous solubility, making organic solvents the preferred choice for calibrant preparation in LC-MS/MS and GC-MS workflows.

Primary Research Applications

Heroin is primarily utilized as a forensic toxicology standard for the identification and quantification of opioids in biological matrices and seized materials . Its applications include method development and validation for LC-MS/MS, HPLC, and GC-MS, as well as confirmatory analysis of biological specimens in clinical toxicology and urine drug testing . The compound also serves as a standard for metabolism research, where its rapid hydrolysis to 6-monoacetylmorphine and morphine is studied . Heroin-D9, a stable-labeled internal standard, is available for quantitative analysis applications .

Storage & Stability

Condition Recommendation
Temperature Store at -20°C for long-term stability 
Light exposure Protect from direct light
Moisture control Keep container tightly sealed; store desiccated 
Handling Use PPE; handle in a fume hood; maintain controlled substance security

For optimal stability, the product should be stored in a freezer in a tightly sealed, desiccated container . Certified reference material solutions in acetonitrile should be stored frozen and brought to room temperature before opening. Due to the volatile nature of the solvent, the solution should be handled promptly after opening to maintain accurate concentration. Researchers must adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances .

Closing Statement

This high-purity certified reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and certified purity values . All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding controlled substances .

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.

Additional information
Quantity

10g

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25g

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50g

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100g

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250g

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500g

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1kg

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