Overview

Ethylone hydrochloride, also known as 3,4-methylenedioxy-N-ethylcathinone or bk-MDEA, is a synthetic cathinone analytical reference standard belonging to the β-keto amphetamine class of compounds . This product is supplied as a high-purity crystalline material for use in forensic and clinical toxicology laboratories. As a structural analog of methylone and the β-keto analogue of MDEA, it serves as an essential reference material for the identification and quantification of cathinone derivatives in seized materials and biological specimens .

Chemical & Physical Properties

The material presents as a white to off-white crystalline solid . For analytical preparation, stock solutions are commonly prepared in methanol or acetonitrile, making it suitable for LC-MS/MS and GC-MS workflows. The crystalline form offers advantages in terms of stability and precise weighing for analytical method development . Ethylone has been identified as a controlled substance in some jurisdictions and is regulated in countries such as Sweden .

Primary Research Applications

Ethylone crystal is primarily utilized as a forensic toxicology standard for the identification and quantification of cathinone derivatives in biological matrices and seized materials . Its primary applications include method development and validation for LC-MS/MS and GC-MS, as well as confirmatory analysis of biological specimens in clinical toxicology and urine drug testing . The compound also serves as a standard for metabolism research and the characterization of emerging cathinone-based stimulants . In vitro studies have shown that ethylone acts as a monoamine transporter substrate, stimulating the release of dopamine and serotonin .

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed container . Certified reference material solutions in methanol or acetonitrile should be handled promptly after opening to maintain accurate concentration. Researchers must adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances.

Closing Statement

This high-purity reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and purity certification. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding synthetic cathinones.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.