Overview

HDEP-28, also known as ethylnaphthidate, is a piperidine-based synthetic stimulant that is structurally related to ethylphenidate, but with its benzene ring replaced by a naphthalene moiety. This product is supplied as a high-purity analytical reference standard for use in forensic and clinical toxicology laboratories. As a compound identified in emerging drug markets since approximately 2015, it serves as an essential reference material for the identification and quantification of phenidate analogs in seized materials and biological specimens.

Chemical & Physical Properties

The material typically presents as a white to off-white powder or crystalline solid. For analytical preparation, stock solutions are commonly prepared in methanol or acetonitrile, making it suitable for LC-MS/MS and GC-MS workflows. HDEP-28 is closely related to HDMP-28, which acts as a potent monoamine reuptake inhibitor.

Primary Research Applications

HDEP-28 is primarily utilized as a forensic toxicology standard for the identification and quantification of phenidate analogs in biological matrices and seized materials. Its primary applications include method development and validation for LC-MS/MS and GC-MS, as well as confirmatory analysis of biological specimens in clinical toxicology and urine drug testing. The compound also serves as a standard for metabolism research and the characterization of emerging phenidate-based stimulants. Certified reference materials are tested under ISO17025 and Guide 34 guidelines for traceability of measurements.

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed container. Certified reference material solutions should be handled promptly after opening to maintain accurate concentration. When stored at -20°C, stock solutions should be used within one month to prevent degradation. Researchers must adhere to standard safe handling practices for hazardous chemicals.

Closing Statement

This high-purity reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and purity certification. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding controlled substances.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.