Overview

Ethylphenidate is a synthetic stimulant belonging to the piperidine class of compounds, structurally analogous to the widely prescribed ADHD medication methylphenidate . This product is supplied as a high-purity powder for use as an analytical reference standard in forensic and clinical toxicology laboratories. As a compound of significant interest in the analysis of novel psychoactive substances, it serves as an essential reference material for the identification and quantification of phenidate analogs in seized materials and biological specimens .

Chemical & Physical Properties

The material presents as a white to off-white crystalline powder. The ethyl ester group in its structure alters the lipophilicity and pharmacokinetic profile relative to methylphenidate . The compound exhibits stereochemical complexity, with the active form primarily associated with the threo-enantiomer .

Primary Research Applications

Ethylphenidate powder is primarily utilized as a forensic toxicology standard for the identification and quantification of phenidate analogs in biological matrices and seized materials . Its applications include method development and validation for LC-MS/MS and GC-MS, as well as confirmatory analysis of biological specimens in clinical toxicology and oral fluid testing . The compound also serves as a standard for metabolism research, where its formation occurs as a metabolite of methylphenidate when co-ingested with ethanol . Certified reference material solutions are available for LC/MS or GC/MS applications such as urine drug testing and forensic analysis .

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed container. Certified reference material solutions should be handled promptly after opening to maintain accurate concentration. Researchers should note that thermal decomposition of phenidate analogs can occur during GC-MS analysis in the injection port .

Closing Statement

This high-purity reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and purity certification. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding phenidate compounds.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.