Overview

(±)-3,4-Methylenedioxymethamphetamine (MDMA) hydrochloride, also known as N-methyl-1-(3,4-methylenedioxyphenyl)propan-2-amine hydrochloride, is a synthetic amphetamine-type analytical reference standard . This product is supplied as a high-purity crystalline material (>98%) for use as a certified reference material in forensic and clinical toxicology laboratories . As a ring-substituted phenethylamine, it serves as an essential standard for the identification and quantification of amphetamine derivatives in biological and seized material samples .

Chemical & Physical Properties

The material presents as a white to off-white crystalline solid with a melting point range of 147–153°C for the hydrochloride salt . Its aqueous solubility makes it readily adaptable for preparing stock solutions and calibrants for various analytical platforms . The crystalline form offers advantages in terms of stability and precise weighing for analytical method development.

Primary Research Applications

MDMA hydrochloride is primarily utilized as a certified reference standard for the identification and quantification of amphetamine-type stimulants in forensic toxicology and clinical research . Its primary applications include method development and validation for LC-MS/MS, HPLC, and GC-MS, as well as urine drug testing and forensic analysis of seized materials . The compound is also used in research exploring the metabolism and analytical detection of substituted phenethylamines, and as a standard for isotope dilution methods in quantitative toxicology .

Storage & Stability

For optimal stability, the product should be stored in a freezer (-20°C) in a tightly sealed, light-resistant container. Proper desiccation is recommended to prevent moisture absorption and maintain the integrity of the analytical standard . Researchers should adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances.

Closing Statement

This high-purity crystalline reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and certified purity values. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding controlled substances.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.