Overview

AB-CHMINACA is a synthetic cannabinoid belonging to the indazole-3-carboxamide class of compounds, first reported in 2013 as a substance found in herbal “Spice” products . This product is supplied as a high-purity crystalline powder for use as an analytical reference standard in forensic and clinical toxicology laboratories. As a potent agonist of the central CB1 receptor, it serves as an essential reference material for the identification and quantification of indazole-based synthetic cannabinoids in seized materials and biological specimens .

Chemical & Physical Properties

The material typically presents as a white to off-white crystalline powder. For analytical preparation, stock solutions are commonly prepared in DMSO, ethanol, or DMF, making it suitable for LC-MS/MS workflows . The compound features a valinamide side chain and a cyclohexylmethyl substituent on the indazole nitrogen, which distinguishes it from related analogs such as ADB-CHMINACA .

Primary Research Applications

AB-CHMINACA is primarily utilized as a certified reference material for the identification and quantification of synthetic cannabinoids in forensic toxicology and clinical research . Its applications include method development and validation for LC-MS/MS, as well as confirmatory analysis of biological specimens in urine drug testing and seized material analysis. The compound undergoes extensive Phase I metabolism, with hydroxylated metabolites serving as key urinary biomarkers for consumption verification . Deuterated internal standards, such as AB-CHMINACA-d4, are available for accurate quantification via isotope dilution mass spectrometry . Certified reference materials are manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards .

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed container . Certified reference material solutions should be handled promptly after opening to maintain accurate concentration. Stock solutions can be stored below -20°C for several months . Researchers must adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances.

Closing Statement

This high-purity certified reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and certified purity values. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding synthetic cannabinoids.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.