Overview

Etizolam Powder is a thienodiazepine derivative belonging to a class of compounds structurally related to benzodiazepines, characterized by a thiophene ring fused to the diazepine core. This product is supplied as a high-purity powder for use as an analytical reference standard in forensic and clinical toxicology laboratories. As a regulated substance in many jurisdictions, it serves as an essential reference material for the identification and quantification of benzodiazepine analogs in seized materials and biological specimens.

Chemical & Physical Properties

The material typically presents as a white to off-white crystalline powder. For analytical preparation, stock solutions are commonly prepared in DMSO or methanol, making it suitable for LC-MS/MS and GC-MS workflows. Certified reference material solutions at 1.0 mg/mL in methanol are available for direct use in analytical applications.

Primary Research Applications

Etizolam powder is primarily utilized as a forensic toxicology standard for the identification and quantification of benzodiazepine analogs in biological matrices and seized materials. Its primary applications include method development and validation for LC-MS/MS and GC-MS, as well as confirmatory analysis of biological specimens in clinical toxicology and urine drug testing. The compound also serves as a standard for metabolism research and multi-residue analysis of sedative-hypnotic compounds. Deuterated internal standards, such as Etizolam-D3, are available for quantitative analysis to ensure accuracy in LC/MS or GC/MS methods.

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed, dry, and dark container. Stock solutions can be stored at 0-4°C for up to one month. Certified reference material solutions in methanol should be handled promptly after opening to maintain accurate concentration. Researchers must adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances.

Closing Statement

This high-purity reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and purity certification. All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding thienodiazepine compounds.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.