Overview

Cocaine hydrochloride is a tropane alkaloid analytical reference standard extracted from the leaves of Erythroxylum coca and other species of the Erythroxylum genus . This product is supplied as a high-purity crystalline solid for use as a certified reference material (CRM) in forensic and clinical toxicology laboratories . As a Schedule II controlled substance in the United States and a regulated compound in many other jurisdictions, it serves as an essential reference material for the identification, quantification, and quality control of cocaine in seized materials and biological specimens .

Chemical & Physical Properties

The material typically presents as a white to off-white crystalline powder . For analytical preparation, stock solutions are commonly prepared in methanol or acetonitrile, making it suitable for LC-MS/MS and GC-MS workflows . The compound exhibits a UV absorption maximum at 231 nm, useful for detection in analytical workflows .

Primary Research Applications

Cocaine hydrochloride is primarily utilized as a certified reference material for the identification and quantification of cocaine in forensic toxicology and clinical research . Its primary applications include method development and validation for LC-MS/MS and GC-MS, as well as confirmatory analysis of biological specimens in urine drug testing, forensic casework, and clinical toxicology . The compound also serves as a standard for metabolism research and multi-residue analysis of illicit substances in hair and blood samples . Certified reference materials are rigorously tested under ISO/IEC 17025 and ISO 17034 accreditation and are available as DEA-exempt preparations .

Storage & Stability

For optimal stability, the product should be stored in a freezer in a tightly sealed container . Certified reference material solutions in acetonitrile or methanol should be handled promptly after opening to maintain accurate concentration . Researchers must adhere to standard safe handling practices for hazardous chemicals and maintain appropriate security for controlled substances.

Closing Statement

This high-purity certified reference material is intended exclusively for in vitro laboratory use in forensic and analytical research. Researchers should consult the Certificate of Analysis (COA) for specific lot data and certified purity values . All handling must be performed within a properly controlled professional laboratory environment, and users must ensure compliance with all local and federal regulations regarding controlled substances.

⚠️ DISCLAIMER:
This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.