Methamphetamine

Overview

Methamphetamine (N-methyl-1-phenylpropan-2-amine) is a controlled, amine-based reference material used in regulated laboratory research and analytical method development. For cataloging and analytical workflows, this compound is commonly referenced by its CAS identifier (CAS number not available unless confirmed by your supplier COA/identity documentation). In forensic chemistry and clinical toxicology contexts, methamphetamine is typically classified as a synthetic/controlled stimulant reference standard and serves as a target analyte for confirmatory identification and quantification. This product is intended for use in controlled laboratory environments to support LC-MS/MS, GC-MS, and related characterization/validation activities, with analytical documentation such as CoA, method notes, and performance specifications.

Chemical & Physical Properties

Methamphetamine reference materials are commonly supplied as a freebase or salt (frequently hydrochloride); the exact form should be confirmed via the provided identity/COA documentation. In analytical workflows, stock solutions are typically prepared using polar organic solvents compatible with LC-MS/MS and GC-MS interfaces (and, when relevant, verified for extraction efficiency and matrix effects). Because solubility and ionization behavior can vary by salt form, laboratory users should align solvent selection and concentration preparation with validated method parameters and analytical QC acceptance criteria.

Primary Research Applications

Methamphetamine is used as an analytical reference standard for forensic toxicology and related clinical toxicology testing, including method development, calibration, and confirmatory analysis. It is commonly employed in LC-MS/MS and GC-MS workflows to establish retention behavior, ion transitions, and quantitative response functions. The compound supports HPLC assay development and can be used for extraction recovery and stability experiments in controlled matrix studies (e.g., urine/blood analogs) following internal validation plans. Additional research uses include analytical method comparability studies, metabolomics target panel development, and reference mapping across instruments and labs, under appropriate regulatory and safety controls.

Storage & Stability

For best analytical performance, store the material tightly sealed to limit moisture uptake and monitor lot-specific conditions provided by the supplier/COA. Prepare working solutions using validated solvents and aliquot where appropriate to reduce repeated freeze-thaw or extended bench exposure. Follow your laboratory’s QA/QC procedures for identity verification, concentration checks against standards where required, and documented stability assessment consistent with your method validation plan.

Closing Statement

Methamphetamine reference standard materials are designed for laboratory research and analytical measurement in accordance with validated forensic and toxicology procedures. Users should consult the product’s COA/analytical report, lot-specific identity information (including salt form), and any stability or storage notes provided by the manufacturer. All handling, solution preparation, and method integration should be performed under your institution’s internal safety protocols and compliance framework for controlled analytes.

⚠️ DISCLAIMER:

This product is sold strictly for laboratory and research purposes only. It is NOT intended for human or veterinary consumption, diagnostic use, or any application involving living organisms. All customers must be qualified and trained laboratory professionals. Buyer assumes all responsibility for safe handling, storage, and legal compliance in accordance with their local, state, and federal regulations. Always use appropriate personal protective equipment (PPE) and work within a properly ventilated fume hood.